Start with the answer
Natural Sciences Managers pay in Massachusetts and South Carolina
The May 2025 BLS OEWS median for Natural Sciences Managers is $267,290 per year in Massachusetts. It is $131,140 per year in South Carolina. Massachusetts is 103.8% above South Carolina on the published median.
Both rows use SOC 11-9121 and the same annual wage metric. Median means the middle of each area's published wage spread. It is not one worker's pay. The larger median is not proof that one place gives a better job or a better result. It is one wage fact from one source period.
BLS lists 10,590 wage and salary jobs in Massachusetts and 780 in South Carolina. Those are survey job counts, not open posts. Read pay, job scale, local share, and price level as separate facts before you make a choice.
Evidence: bls-oews-may-2025 · Rule: same-soc-same-metric-pair · nominal-median-gap · employment-not-openings